Use of drugs with anticholinergic effects and cognitive impairment in community-living older persons.

نویسندگان

  • Reshma A Merchant
  • Bintao Li
  • Keng-Bee Yap
  • Tze-Pin Ng
چکیده

‘Acopia’ is a pejorative term describing the older patient who is ‘unable to cope’. This study assessed the characteristics of patients presenting with ‘acopia’ to a district general hospital in the United Kingdom. Nearly half of ‘acopia’ patients presented with geriatric syndromes such as falls and confusion. Redefining ‘acopia’ as an all-encompassing term to describe the frail older patient with multiple medical problems may help identify patients in need of urgent specialist geriatric input.

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منابع مشابه

[Effect of anticholinergic drugs on cognitive impairment in the elderly].

The use of anticholinergic drugs is common in the elderly, even in people with cognitive impairment. A systematic search was conducted in PubMed (anticholinergic effects, anticholinergic and dementia) to define the effects of anticholinergic drugs in the elderly. We emphasized the search in patterns of use, the combined use with AChEIs, the measurement of the Serum Anticholinergic Activity, and...

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Drugs with anticholinergic properties, cognitive decline, and dementia in an elderly general population: the 3-city study.

BACKGROUND Despite the high intake of medications with anticholinergic properties by community-dwelling elderly persons, the effects on cognitive decline and dementia have rarely been evaluated. METHODS Participants were 4128 women and 2784 men 65 years or older from a population-based cohort recruited from 3 French cities. Cognitive performance, clinical diagnosis of dementia, and anticholin...

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Prevalence of Cognitive Impairment in Community-Dwelling Older Adults

Introduction: Mild cognitive impairment can be considered as an intermediate clinical state between normal cognitive aging and mild dementia. Elderly people with this impairment represent an at-risk group for the development of dementia. The aim of this study was to investigate the prevalence of cognitive impairment in community-dwelling older adults by Mini-Mental State Examination (MMSE) and ...

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Anticholinergic medication use and cognitive impairment in the older population: the medical research council cognitive function and ageing study.

OBJECTIVES To determine whether the use of medications with possible and definite anticholinergic activity increases the risk of cognitive impairment and mortality in older people and whether risk is cumulative. DESIGN A 2-year longitudinal study of participants enrolled in the Medical Research Council Cognitive Function and Ageing Study between 1991 and 1993. SETTING Community-dwelling and...

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Cognitive Decline in Older Persons Initiating Anticholinergic Medications

BACKGROUND This study examines the effect of initiating medications with anticholinergic activity on the cognitive functions of older persons. METHODS Participants were 896 older community-dwelling, Catholic clergy without baseline dementia. Medication data was collected annually. The Anticholinergic Cognitive Burden Scale was utilized to identify use of a medication with probable or definite...

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عنوان ژورنال:
  • Age and ageing

دوره 38 1  شماره 

صفحات  -

تاریخ انتشار 2009